The National Institute of Health (NIH) has issued a high alert following the confirmation of H3N2 “super flu” cases across Pakistan.
According to the NIH, a more dangerous H3N2 sub-clade known as “K” is spreading rapidly in the country. Surveillance data shows that 20 per cent of circulating H3N2 samples belong to this aggressive sub-clade.
In response to the growing threat, the NIH has directed federal and provincial health departments to remain on high alert amid a sharp rise in influenza cases.
Early and Unusual Surge
Pakistan is witnessing an unusually early surge in seasonal influenza. Since May 2025, around 66 per cent of reported Influenza A cases have been linked to H3N2.
NIH surveillance further indicates that over 340,000 suspected flu cases have been reported nationwide during the past six weeks. Laboratory testing shows that 12 per cent of samples tested positive for H3N2.
Hospitals have been instructed to prepare for an increase in outpatient visits and hospital admissions, as health officials warn that flu cases are likely to rise further during the winter months.
High-Risk Groups Identified
The NIH warned that the H3N2 virus poses a greater risk to elderly people, children, and pregnant women. Patients suffering from diabetes, heart disease, and respiratory illnesses are also considered highly vulnerable.
Health authorities noted that overcrowded areas and poorly ventilated indoor spaces are significantly contributing to the rapid spread of the virus.
Preventive Measures and Treatment
The NIH has called for stricter infection control measures nationwide and emphasized that seasonal influenza vaccination remains an effective tool to prevent severe illness and deaths. The institute confirmed that the currently available flu vaccine is effective against the H3N2 sub-clade “K.”
Early antiviral treatment has been strongly recommended for high-risk patients, with officials warning that delays can lead to pneumonia and respiratory failure.
The public has been urged to adopt precautionary measures and ensure timely vaccination to curb the spread of the virus.



